Ex parte DEBRAUWERE et al. - Page 5




                 Appeal No. 1996-2963                                                                                     Page 5                        
                 Application 07/952,427                                                                                                                 


                 less than or equal to 6.3.”  The representative claim  does                                    2                                       
                 not explicitly require that any portion of the container is                                                                            
                 constructed of a non-PVC material.                                                                                                     
                          Mohr (page 4) describes a method for inactivating viruses                                                                     
                 using a dye such as methylene blue in the treatment of blood                                                                           
                 in a blood bag.  Mohr teaches a pH value between 5 and 8,                                                                              
                 preferably between 6 and 8 (Mohr, pages 4 and 5), a disclosed                                                                          
                 pH value overlapping the claimed range.  Hence, as explained                                                                           
                 by the examiner (answer, page 4), Mohr discloses a steam                                                                               
                 sterilizable container (blood bag) containing an amount of                                                                             
                 methylene blue solution corresponding to the herein claimed                                                                            
                 therapeutically effective amount.  According to the examiner                                                                           
                 (answer pages 4 and 5), it would have been obvious to one of                                                                           
                 ordinary skill in the art to select a methylene blue solution                                                                          
                 with a pH corresponding to the herein claimed pH value of less                                                                         
                 than or equal to 6.3 in light of Mohr’s disclosure of using pH                                                                         
                 value ranges that are inclusive of pH values below 6.3.  We                                                                            
                 agree.                                                                                                                                 


                          2We note that appealed claim 18, likewise, does not                                                                           
                 specify non-PVC material not withstanding the argument of                                                                              
                 appellants to the contrary (brief, page 10).                                                                                           
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