Appeal No. 1996-3409
Application No. 08/092,543
DECISION ON APPEAL
This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 1 through
20, all the claims remaining in the application.
Claims 1 and 10 are representative:
1. In a method for diagnosing disorders in a test individual in which fluid
samples from normal unafflicted control individuals, afflicted abnormal
individuals and said test individuals are analyzed to generate electrical
signal patterns representative of molecular constituents of said samples, the
improvement which comprises creating a data base of electrical signal
patterns representative of frequency distribution of a plurality of
predetermined molecular constituents of fluid samples from an
epidemiologically significant number of individuals having known categories
of disorders and from said unafflicted control individuals, and comparing
said electrical signal patterns in said data base for conformity to electrical
signal patterns representative of frequency distribution of said
predetermined molecular constituents of a fluid sample from said test
individual.
10. A method according to claim 1, wherein said fluid samples comprise
electrochemically active compounds, and wherein each electrical signal
pattern representative of frequency distribution of said plurality of
predetermined constituents of said fluid samples is generated by the
following steps, comprising:
passing each one of said fluid samples separately through a liquid
chromatographic column for achieving time-space separation of the
electrochemically active compounds of said fluid sample eluting in the
column and generating electrical signals representative of the
electrochemical pattern of said fluid sample using an electro-
chemical detection apparatus.
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