Ex parte STARNES - Page 3




              Appeal No. 1997-0467                                                                                         
              Application 08/318,019                                                                                       



                                                     DISCUSSION                                                            
                     In resolving questions of obviousness, a decision-maker must consider the claimed                     
              subject matter as a whole.  35 U.S.C. § 103.  Here, independent claim 15 recites a                           
              process of treating a liquefied starch solution with cyclodextrin glycosyl transferase                       
              “wherein the cyclodextrin glycosyl transferase used in the treatment is derived from a strain                
              of Clostridium and has a pH optimum of about 5.0 and a temperature optimum in the range                      
              of 80-85EC.”    Further, according to claim 15, the treating step is carried out “at a                       
              temperature above 70EC.”  Manifestly, the Maize reference relied on by the examiner                          
              constitutes insufficient evidence to support a conclusion of obviousness of claims                           
              containing those limitations.                                                                                
                     The Maize disclosure, like applicant's specification, relates to a process for                        
              enzymatically converting a liquefied starch solution to cyclodextrin using cyclodextrin                      
              glycosyl transferase.  Maize, however, discloses cyclodextrin glycosyl transferase                           
              produced by Bacillus unlike applicant's cyclodextrin glycosyl transferase “derived from a                    
              strain of Clostridium” having “a pH optimum of about 5.0 and a temperature optimum in the                    
              range of 80-85EC.”  See the Maize reference (English translation), page 1, second and                        
              third paragraphs; paragraph bridging pages 2 and 3; and page 4, third full paragraph.                        
              Further, Maize discloses that cyclodextrinization “is carried out at 30-65EC” (page 3, fourth                
              full paragraph) whereas claim 15 requires “a temperature above 70EC.”  On this record,                       

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