Appeal No. 1997-0467 Application 08/318,019 DISCUSSION In resolving questions of obviousness, a decision-maker must consider the claimed subject matter as a whole. 35 U.S.C. § 103. Here, independent claim 15 recites a process of treating a liquefied starch solution with cyclodextrin glycosyl transferase “wherein the cyclodextrin glycosyl transferase used in the treatment is derived from a strain of Clostridium and has a pH optimum of about 5.0 and a temperature optimum in the range of 80-85EC.” Further, according to claim 15, the treating step is carried out “at a temperature above 70EC.” Manifestly, the Maize reference relied on by the examiner constitutes insufficient evidence to support a conclusion of obviousness of claims containing those limitations. The Maize disclosure, like applicant's specification, relates to a process for enzymatically converting a liquefied starch solution to cyclodextrin using cyclodextrin glycosyl transferase. Maize, however, discloses cyclodextrin glycosyl transferase produced by Bacillus unlike applicant's cyclodextrin glycosyl transferase “derived from a strain of Clostridium” having “a pH optimum of about 5.0 and a temperature optimum in the range of 80-85EC.” See the Maize reference (English translation), page 1, second and third paragraphs; paragraph bridging pages 2 and 3; and page 4, third full paragraph. Further, Maize discloses that cyclodextrinization “is carried out at 30-65EC” (page 3, fourth full paragraph) whereas claim 15 requires “a temperature above 70EC.” On this record, 3Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007