Ex parte HOCK et al. - Page 2




                Appeal No. 1997-1093                                                                                                            
                Application No. 08/272,281                                                                                                      


                amended subsequent to the final rejection, which are all of the claims pending in this                                          
                               2                                                                                                                
                application.   Claim 1 is illustrative and reads as follows.                                                                    
                                 1.  A processed stable fibrinogen solution, obtained by                                                        
                         a)      treating a starting fibrinogen solution at least twice with an adsorbent                                       
                                 selected from the group consisting of an anion exchanger, a sparingly                                          
                                 soluble salt of an alkaline earth metal and aluminum hydroxide,                                                
                         b)      removing said adsorbent from the treated fibrinogen solution leaving                                           
                                 a supernatant, wherein the fibrinogen remains in said supernatant                                              
                                 and                                                                                                            
                         c)      recovering said supernatant,                                                                                   
                         wherein the fibrinogen in the supernatant maintains its ability to function                                            
                         when stored at 4-25EC for four weeks.                                                                                  
                         The references relied on by the examiner are:                                                                          
                Kotitschke et al.  (Kotitschke)                    4,272,523                 Jun.  9, 1981                                      
                Rose et al.  (Rose)                                4,627,879                 Dec.  9, 1986                                      
                Mathews et al.  (Mathews)                          4,743,680                 May 10, 1988                                       
                                                                  ISSUES                                                                        
                         Claims 1-3, 5, 7, 9, and 11-13 stand rejected under 35 U.S.C. § 103 as being                                           
                unpatentable over Kotitschke in view of Mathews.  Claims 8, 10, and 14 stand rejected                                           
                under 35 U.S.C. § 103 as being unpatentable over Kotitschke in view of Mathews as                                               
                applied to claims 1-3, 5, 7, 9, and 11-13, and further in view of Rose.                                                         


                         2The amendment filed October 27, 1995 (Paper No. 19) amending claims 1 and 9 was entered by                            
                the examiner in the advisory action mailed December 6, 1995 (Paper No. 21).                                                     
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