Ex parte KOSLEY JR. et al. - Page 14




          Appeal No. 1997-2182                                                        
          Application 08/137,443                                                      
          appellants must rebut the position taken by the examiner.                   
               As we have noted above, on balance, the evidence on which              
          the examiner has relied gives credence to the objective                     
          truthfulness of appellants' representations rather than casts               
          doubt on them.  Moreover, the examiner has improperly narrowly              
          construed appellants' claims as limited to the treatment of                 
          Alzheimer's disease.  Both the claims and appellants'                       
          disclosure are directed generally to treating a type of memory              
          dysfunction in mammals characterized by decreased cholinergic               
          function.  The very art on which the examiner relies suggests               
          that at the time appellants made their invention, AChE                      
          inhibitors were generally recognized as a class of compounds                
          suitable for treating illness attributable to decreased                     
          acetylcholine function, including Alzheimer's disease.                      
               The examiner also expresses his belief that the prior art              
          on which he has relied establishes that there was, at the time              
          of appellants' invention, no known cure or even treatment for               
          Alzheimer's disease.  In the first instance, as we have stated              
          above, appellants do not claim either a cure of or even                     
          treatment for Alzheimer's disease but claim a method for                    
          treating a specific type of memory dysfunction.  Secondly, the              
          operative claim term used is "treating" by administration of                
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