Ex parte MINNICH et al. - Page 4



             Appeal No. 1997-2389                                                                                
             Application No. 08/987,233                                                                          


                   The references relied upon by the examiner are:                                               
             Sadowski                                4,443,549                 Apr. 17, 1984                     
             Fernwood et al. (Fernwood)              4,493,815                 Jan. 15, 1985                     
             Mattiasson                              4,592,994                 Jun.   3, 1986                    
             Jolley                                  4,652,533                 Mar. 24, 1987                     
             Feng et al. (Feng), “Fluorogenic Assays for Immediate Confirmation of Escherichia Coli,”            
             Applied and Environmental Microbiology, Vol. 43, No. 6, pp. 1320-1329 (1982).                       
             Singer et al. (Singer), “Optimization of in situ Hybridization Using Isotopic and Non-Isotopic      
             Detection Methods,” BioTechniques, Vol. 4, No. 3, pp. 230-243 (1986).                               
                                             Grounds of Rejection                                                

                   Claims 27, 28, 31 - 35, 43, and 47 stand rejected under 35 U.S.C. § 103.  As                  
             evidence of obviousness, the examiner relies upon Jolley, Fernwood, and Mattiasson.                 
                   Claims 29, 30, 36 - 42, and 44 - 46 stand rejected under 35 U.S.C. § 103.  As                 
             evidence of obviousness, the examiner relies upon Jolley, Fernwood, Mattiasson, Feng,               
             Sadowski, and Singer.                                                                               
                                                  Discussion                                                     

                   In reaching our decision in this appeal, we have given careful consideration to the           
             appellants' specification and claims and to the respective positions articulated by the             
             appellants and the examiner.  We make reference to the Examiner's Answer (Paper No.                 
             31) for the examiner's reasoning in support of the rejections and to the appellants' Appeal         
             Brief (Paper No. 30) for the appellants' arguments thereagainst.                                    






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