Ex parte SHIBLEY et al. - Page 12




              Appeal No. 1997-2512                                                                                           
              Application No. 08/118,905                                                                                     

              See column 3, lines 40-56.  At column 6, lines 24-26, Frenkel teaches: “In addition, while                     
              the bradyzoite cysts have been fed directly, if desired the vaccine may include a suitable                     
              carrier.”                                                                                                      
                      However, in contrast to the subject matter of independent claim 12, from which                         
              claims 14 and 15 depend, Frenkel does not disclose or suggest the following:                                   

                      1.     “providing a tube containing said biological or pharmaceutical material";                       
                      2.     “which tube is sealed at its ends and is administered to an intended cite                       
                             [sic, site] of the animal”;                                                                     
                      3.     “by penetrating the sealed tube at its lower section";                                          
                      4.     “followed by penetrating the tube at its upper section";                                        
                      5.     “to release the material to the mucosal membrane of the animal.”                                
                      Recognizing the deficiencies of Frenkel, the examiner relies on Whittaker to show                      
              that one of ordinary skill in the art would have been motivated to modify Frenkel’s method                     
              by using the delivery device disclosed in Whittaker.  As we discussed supra, however,                          
              Whittaker fails to disclose claim elements 3 to 5 above.  Nor is there any evidence to show                    
              that one of ordinary skill in the art would have found the appellants’ claimed administration                  
              technique to have been an obvious variation of Whittaker’s administration step (i.e.,                          
              expulsion of the medicinal fluid by allowing compressed air generated from the squeezing                       

              of a bulb to act on a plug that performs the function of a piston).  Therefore, even if Frenkel                
              and Whittaker were to be combined as suggested by the examiner, the combination would                          



                                                             12                                                              



Page:  Previous  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  Next 

Last modified: November 3, 2007