Appeal No. 1997-2569 Application No. 08/469,578 The examiner recognizes that both Gibbs and Lee fail to teach using electrostatic or acoustic energy to effect the mixing disclosed therein. Nevertheless, the examiner concludes (Answer, pp. 4-5): It would have been obvious to one of ordinary skill in the art at the time the invention was made to provide a vibratory agitator in place of the air- driven agitator in the device of Gibbs because vibratory agitators achieve mixing in droplets on moving test strips as taught by Lee. It would have been obvious to one of ordinary skill in the art at the time the invention was made to provide a sonic source as the vibratory agitator in the modified device of Gibbs and Lee because a sonic source is suitable for reagent mixing by vibration as taught by Woodbridge. Appellants argue that the combination of Gibbs, Lee and Woodbridge proposed by the examiner amounts to a hindsight reconstruction of the claimed invention. First, appellants argue that there is no motivation to use vibratory agitation as in Lee to mix the droplets in Gibbs since Lee uses a gel which confines the droplets during mixing. Particularly, appellants argue (Brief, p. 6): The forces acting on the drop of whole blood in Lee are significantly greater than those found in Gibbs. The skilled artisan could reasonably conclude that vibratory mixing of the type used by Lee would not work for the drop of liquid in Gibbs. 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007