Ex parte RIESS et al. - Page 6




              Appeal No. 1997-2742                                                                                         
              Application 08/348,815                                                                                       





              we believe that more is required to provide enabling support for claims drawn to in vivo                     
              methods for controlling H. pylori infection in a patient.  Again, it was known at the time the               
              invention was made that “H. pylori is very sensitive to a wide range of antibiotics in vitro.                
              Unfortunately, when used as a treatment in vivo few are effective.” (Axon, page 65, first                    
              paragraph).  On this record, appellants have not established that moenomycin or its                          
              derivatives are effective in vivo for controlling H. pylori infection.                                       
                     The rejection of claims 7, 8, 10 and 11 under 35 U.S.C. §112, first paragraph, is                     
              affirmed.                                                                                                    


                                                     CONCLUSION                                                            

                     In conclusion, the rejection of claims 7 through 12 under 35 U.S.C. § 103 as                          
              unpatentable “over Welzel et al. or Huber in combination with Axon” is reversed.  The                        
              rejection of claims 7, 8, 10 and 11 under 35 U.S.C. § 112, first paragraph, as based on a                    
              non-enabling disclosure, is affirmed.  Accordingly, the examiner’s decision is affirmed-in-                  
              part.                                                                                                        





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