Appeal No. 1997-2926 Application No. 08/376,299 dried microorganisms “overcomes the shortcomings of a culture of microorganisms which are transported from the manufacture to the area of use in a liquid medium (See column 1, line 60 to column 2, line 3).” (Answer, page 9). We do not agree that Hoffmann discloses or suggests “substantially the same” method as recited by the claimed subject matter. Hoffmann does not disclose or suggest that the use of freeze-dried microorganisms “overcomes the shortcomings” of transporting a liquid medium (see col. 1, ll. 60-68). Hoffmann merely discloses freeze-drying or lyophilizing as another technique presently used for preserving the activity of bacteria (col. 1, l. 68-col. 2, l. 3). Furthermore, Hoffmann does not disclose or teach transporting bacteria in lyophilized form wherein the bacteria are reconstituted at the treatment site (see the Answer, page 4). Hoffmann only discloses that a drawback of freeze-drying bacteria is that the “freeze-dried bacteria need to be rehydrated prior to achieving optimal activity.” (Col. 2, ll. 13-15). Hoffmann is silent as to where the rehydration occurs. “Where the legal conclusion [of obviousness] is not 4Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007