Ex parte KING et al. - Page 3




                 Appeal No. 1997-3461                                                                                     
                 Application No. 07/806,932                                                                               
                     Claims 22, 23, 25 and 26 are provisionally rejected under the judicially created                     
              doctrine of obviousness-type double patenting as being unpatentable over claims 1-4                         
              of copending application Steeg II in view of Mullis.3                                                       

                     Claims 22, 23, 25 and 26 are rejected under 35 U.S.C. ' 103 as being                                 

              unpatentable over Steeg I in view of Mullis, or the combination of Steeg III and                            
              Bevilacqua in view of Mullis.                                                                               
                     We reverse.                                                                                          
                                                   DISCUSSION                                                             
                     In reaching our decision in this appeal, we have given careful consideration to                      
              the appellants’ specification and claims, and to the respective positions articulated by                    
              the appellants and the examiner.  We make reference to the examiner=s Answer (Paper                         

              No. 32, mailed May 10, 1996), for the examiner=s reasoning in support of the rejection.                     

              We further reference appellants’ Brief (Paper No.  31, filed February 21, 1996) and                         
              appellants’ Reply Brief (Paper No. 33, filed July 10, 1996), for the appellants’                            
              arguments in favor of patentability.                                                                        
                     The examiner’s basis for each rejection is that the cDNA sequence for murine                         
              nm23 is known, this murine cDNA sequence has been shown to detect human nm23,                               
              and the prior art recognizes that nm23 is differentially expressed in low vs. high                          
              metastatic cells.  See, Answer, pages 4-6.  The examiner therefore reasons that an                          

                                                                                                                          
              3  We note the examiner’s reference to 08/048,136, matured into Re. 35,097, therefore                       
              this rejection is no longer provisional.                                                                    
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