Ex parte ROSENBLUM et al. - Page 4




                   Appeal No. 1997-3542                                                                                                                             
                   Application No. 08/192,507                                                                                                                       


                   3.       Claims 1, 2, 6, 7, 11, 12, 16 and 17 stand rejected under 35 U.S.C. § 103 over                                                          
                   Julius and Kung, taken with Lambert and Taylor.                                                                                                  
                   4.       Claims 3, 4, 14 and 15 stand rejected under 35 U.S.C. § 103 over Julius and Kung,                                                       
                   taken with Lambert and Taylor and further in view of De Clercq.                                                                                  
                   5.       Claims 5 and 13 stand rejected under 35 U.S.C. § 103 over Julius and Kung, taken                                                        
                   with Lambert and Taylor, as applied to claims 1, 2, 5-7, 11-13, 16 and 17, and further in                                                        
                   view of Brady.                                                                                                                                   
                                                                DECISION ON APPEAL                                                                                  
                   35 U.S.C. § 112, first paragraph                                                                                                                 
                            The specification is objected to and claims 3 and 14 stand rejected under 35                                                            
                                                                                              1, 2                                                                  
                   U.S.C. § 112, first paragraph for lack of enablement.                                                                                            
                            In the present case, the rejected claims are directed to an anti-IgM antibody                                                           
                   conjugate wherein the antibody portion of the conjugate is produced from specific                                                                
                   hybridoma, i.e., 2G10 (claim 3) and 1C2 (claim 14).  It is the examiner’s position that the                                                      
                   methods set forth in the specification will not necessarily reproduce antibodies and                                                             
                   hybridomas which are chemically and structurally identical to those claimed.    Furthermore,                                                     

                            1The Answer has withdrawn a rejection of claims 5, 7, 13 and 17 under 35 U.S.C.                                                         
                   § 112, first paragraph for lack of enablement.   Answer, page 3.                                                                                 
                            2The Answer, page 8 contains a typographical error, and inaccurately indicates                                                          
                   claims 3 and 4 are rejected under 35 U.S.C. § 112, first paragraph for lack of enablement                                                        
                   instead of claims 3 and 14, as set forth in the final rejection, Paper No. 5, page 2.                                                            
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