Ex Parte KOSTERS - Page 4



                 Appeal No. 1998-2047                                                                                     
                 Application No. 08/400,559                                                                               


                 known, and that S. cepivorum was known soil-borne plant pathogen.  The                                   
                 examiner also relied on the specification’s admission that S. cepivorum was                              
                 known to infect onions.  The examiner concluded that the prior art would have                            
                 motivated the skilled artisan to practice the claimed invention with a reasonable                        
                 expectation of success.                                                                                  
                         “It is well-established that before a conclusion of obviousness may be                           
                 made based on a combination of references, there must have been a reason,                                
                 suggestion, or motivation to lead an inventor to combine those references.”                              
                 Pro-Mold & Tool Co. v. Great Lakes Plastics Inc., 75 F.3d 1568, 1573,                                    
                 37 USPQ2d 1626, 1629 (Fed. Cir. 1996).                                                                   
                         Although couched in terms of combining teachings found in the                                    
                         prior art, the same inquiry must be carried out in the context of a                              
                         purported obvious “modification” of the prior art. The mere fact that                            
                         the prior art may be modified in the manner suggested by the                                     
                         Examiner does not make the modification obvious unless the prior                                 
                         art suggested the desirability of the modification.                                              
                                                                                                                         
                 In re Fritch, 972 F.2d 1260, 1266, 23 USPQ2d 1780, 1783-84 (Fed. Cir. 1992).                             
                         Here, the examiner has concluded that it would have been obvious to                              
                 modify the prior art methods by applying cyproconazole to allium seeds rather                            
                 than to allium plants.  The examiner found motivation to so modify the prior art to                      
                 be provided by Smith, who teaches that S. cepivorum is an “important soil-borne                          
                 pathogen.”  We do not agree that Smith would have motivated those skilled in the                         
                 art to treat allium seeds with cyproconazole.  While Smith teaches that S.                               
                 cepivorum is a known plant pathogen, she does not identify onions or other                               


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