Ex parte MILLER et al. - Page 5


                  Appeal No. 1998-3386                                                                                        
                  Application No. 08/265,698                                                                                  
                  Aramide Maatschappij v.o.f. v. United States Int=l Trade Comm=n, 808 F.2d 1471,                             

                  1481, 1 USPQ2d 1241, 1246 (Fed. Cir. 1986).  The Lackner reference is directed                              
                  to demonstrating “the involvement of Mn3+ and manganese peroxidase in the                                   

                  biodegradation of chlorolignin by P. chrysosporium” (Lackner, page 1093, first full                         
                  paragraph).  Thus in contrast to the examiner’s position, the whole purpose of the                          
                  dialysis tubing in Lackner was to separate some of the reagents involved in the                             
                  biodegradation of chlorolignin to identify the active agents.  For example, Lackner                         
                  state (page 1095) “[t]herefore, it seemed likely that mycelium bound manganese                              
                  peroxidase might play an important role in bleach plant effluent degradation.  To                           
                  show this, we performed subsequent experiments during which the high molecular                              
                  weight chlorolignin was not added directly to the cultures but packed into dialysis                         
                  tubings….”  In fact, Lackner teach (page 1094) the lignin, “waste,” and the                                 
                  peroxidase together in a “semicontinuous culture.”  Thus, in contrast to the                                
                  examiner’s position, it appears to us that removing the tubing would not defeat “the                        
                  whole purpose of Lackner.”                                                                                  
                         We remind the examiner that “it is impermissible within the framework of                             
                  section 103 to pick and choose from any one reference only so much of it as will                            
                  support a given position to the exclusion of other parts necessary to the full                              
                  appreciation of what such reference fairly suggests to one skilled in the art.”  In re                      
                  Wesslau, 353 F.2d 238, 241, 147 USPQ 391, 393 (CCPA 1965); see also In re                                   
                  Mercier, 515 F.2d 1161, 1165-66, 185 USPQ 774, 778 (CCPA 1975).  Instead,                                   
                  obviousness can only be established by combining or modifying the teachings of the                          



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