Appeal No. 1999-2200 Application No. 08/896,063 Without a cDNA having the claimed sequence, a method of assaying as claimed can not be reasonably expected. Therefore, in our opinion, the examiner failed to meet her burden of establishing a prima facie case of obviousness. Where the examiner fails to establish a prima facie case, the rejection is improper and will be overturned. In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). Having determined that the examiner has not established a prima facie case of obviousness, we find it unnecessary to discuss the Kamboj Declaration77, executed August 7, 1997, under 37 CFR § 1.131, relied on by appellants to rebut any such prima facie case. Accordingly we reverse the rejection of claims 22, 23, and 34-38 under 35 U.S.C. §103 over Keinanen in view of Sommer ’90 and McNamara. Summary: We reverse the examiner’s rejection of claims 22-23 and 34-38 under 35 U.S.C. § 103 as being unpatentable over Keinanen in view of Sommer ’90 and McNamara. REVERSED THE NMDA CLASS OF GLUTAMATE RECEPTORS 77 However, we note the examiner’s statement (Answer, page 17) “[t]he Rule 1.131 declaration submitted by [a]ppellants would only be sufficient to effectively establish reduction to practice prior to McNamara for the teaching that there is conservation between the human GluR1-3 compared to rat GluR1-5 as well as human EAA1a and EAA2a receptors, but no additional teaching.” 103Page: Previous 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 NextLast modified: November 3, 2007