Interference 102,413 Page 29
Pitha v. Muller
various drugs. We have not been directed to evidence which41
establishes that the product Sz-11 contained cyclodextrin
derivatives as required by the count. Thus, the products
Sz-32, Sz-36 and Sz-40, all of which incorporate Sz-11, fail
to describe an embodiment which falls within the scope of the
count.
c. The product Sz-20 and products including Sz-20
In Sz-20 (PR 173-174 reproduction of PX-19-30), the
experiment took place no later than July 2, 1981, which is the
date indicated on the subsequently occurring page PX-19-37.
The oxymercuration-demercuration of hydroxypropyl-beta-
cyclodextrin was described by the experiment. The substance
is described as a light yellow, glass powder like substance
with no crystals. There is no indication whether the product
of Sz-28 contained more than one cyclodextrin derivative. The
solubility of the substance in water at 20 C is reported to be o
15.8 g/100ml.
In SZ-32 (PX-19-44), the product produced from Sz-20 was
solubilized in water with Vitamin A (retinol) and Vitamin D
3.
The experiment took place no later than July 14, 1981, which
is the date indicated on the next occurring page PX-19-45.
41PR page 182, lines 9-14, page 185, lines 4-10, page
185 line 19 to page 186 line 6, and page 187, lines 4-9.
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