Ex parte STROM et al. - Page 3


                Appeal No.  2000-0839                                                                         
                Application No. 08/355,502                                                                    


                                                DISCUSSION                                                    
                      In reaching our decision in this appeal, we considered appellants’                      
                specification and claims, in addition to the respective positions articulated by the          
                appellants and the examiner.  We make reference to the examiner’s Answer2 for the             

                examiner’s reasoning in support of the rejections.  We further reference appellants’          
                Brief3, and Reply Brief4 for the appellants’ arguments in favor of patentability.  We         
                note the examiner entered and considered appellants’ Reply Brief.5                            

                THE REJECTIONS UNDER 35 U.S.C. § 103:                                                         
                Claims 1, 2, 4 and 8-10:                                                                      
                      According to the examiner (Answer, page 4) Capon teach:                                 
                             chimeric proteins for directing ligand binding partners such as                  
                             growth factors, hormones or effector molecules to cells bearing                  
                             ligands for the ligand binding partners comprising a ligand                      
                             binding partners fused to a stable plasma protein which is                       
                             capable of extending the in vivo half-life of the loigand binding                
                             partner when present as a fusion with the ligand binding                         
                             partner, in particular wherein such a stable plasma protein is                   
                             an immunoglobulin constant domain.                                               
                      While the examiner does not expressly recognize this fact, Capon does not               
                teach IL-10.  The examiner applies Mosmann to make up for this deficiency in                  
                Capon.  According to the examiner (Answer, bridging paragraph, pages 4-5)                     




                                                                                                              
                2 Paper No. 26, mailed October 14, 1999.                                                      
                3 Paper No. 25, received September 14, 1999.                                                  
                4 Paper No. 28, received December 6, 1999.                                                    
                5 Paper No. 29, mailed February 22, 2000.                                                     

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