Ex parte RITTERSHAUS - Page 9


              Appeal No. 2000-1812                                                                                        
              Application No. 08/432,483                                                                                  

              claimed invention.  However, what is missing from the examiner’s rejection of claims 1, 2,                  
              6 - 8 and 27 is a teaching or suggestion to be found in the prior art which would have                      
              reasonably led those of ordinary skill in this art to the claimed invention.  That Swenson and              
              Valmori may, individually, describe components of the claimed invention, in the absence of                  
              evidence or facts which would reasonably suggest the modification of the explicit teaching                  
              of these references, would not have led one of ordinary skill to the claimed invention since                
              the prior art does not suggest the desirability of the modification.  In re Gordon, 733 F.2d                
              900, 902, 221 USPQ 1125, 1127 (Fed. Cir. 1984).  In re Fritch, 972 F.2d 1260, 1266,                         
              n.14, 23 USPQ2d 1780, 1783-84, n.14 (Fed. Cir. 1982).                                                       
                     In the absence of such evidence, the only suggestion to prepare a hybrid peptide as                  
              presently claimed in claims 1, 2, and 27 and to incorporate such a peptide into a vaccine                   
              composition as claimed in claims 6, 7, and 8, is provided by appellant's disclosure of the                  
              invention.  However, use of this information as a basis for establishing a prima facie case                 
              of obviousness, within the meaning of 35 U.S.C. § 103, would constitute impermissible                       
              hindsight.  There must be some reason, suggestion, or  motivation found in the prior art                    
              whereby a person of ordinary skill in the field of the invention would make the modifications               
              required.  That knowledge can not come from the applicant’s invention itself.   Diversitech                 
              Corp. v. Century Steps, Inc.,  850 F.2d 675, 678-79,  7 USPQ2d 1315, 1318 (Fed. Cir.                        
              1988); In re Geiger, 815 F.2d 686, 688, 2 USPQ2d 1276, 1278 (Fed. Cir. 1987);                               
              Interconnect Planning Corp. v. Feil, 774 F.2d 1132, 1143,  227 USPQ 543, 551 (Fed. Cir.                     
              1985).  Thus, on this record, the examiner has not provided those facts or evidence which                   
              would reasonably support a conclusion that the claimed subject matter would have been                       


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