Appeal No. 1995-3965 Application No. 07/719,005 hybridization.” Therefore, appellants conclude (Answer, page 17) that “[w]hen considering the above-described fundamental difference as a whole, it is crucial to note that Kimmel provides absolutely no suggestion of any technique which would enable the detection of more than one microorganism using a single incubation/hybridization.” In response the examiner argues (Answer, pages 8 and 9) that appellants admit, “in Paper 16, filed May 10, 1993 ‘that the laboratory procedures required to carry out the reverse hybridization technique are well known and are fully disclosed in Wang et al.’” We are not persuaded by this argument. While “laboratory procedures” (e.g., Southern Blot procedures) may be well known, it is the claimed invention as a whole that must be considered in an obviousness determination. See In re Antonie, 559 F.2d 618, 625, 195 USPQ 6, 8 (CCPA 1977). Furthermore, as set forth in In re Nomiya, 509 F.2d 566, 571, 184 USPQ 607, 612 (CCPA 1975) “[t]he court must be ever alert not to read obviousness into an invention on the basis of the applicant’s own statements; that is, we must view the prior art without reading into that art appellant’s teachings.” The examiner also argues (Answer, pages 9-10) that “Kimmel explicitly teaches the same principle as found in this application, namely, that one could mix probes of different DNA species and use this probe mixture to simultaneously detect complementary DNA of several different species by hybridizing to multiple spots … with a single hybridization….” Thus the examiner concludes (Answer, bridging sentence, pages 10-11), “[t]aken together with the Wang et al. procedure, 6Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007