Ex parte LIPPS - Page 5




              Appeal No. 1997-2639                                                                                      
              Application No. 08/237,129                                                                                


              venom is a growth factor which would be useful in wound healing.  Answer, page 5.  It is                  
              noteworthy that during the oral hearing on January 11, appellant also stipulated that the $-              
              taipoxin used in the method of appellant and that of Lind are the same.                                   
                     The examiner finds that Siigur evidences that Vipera berus berus venom is a                        
              source for nerve growth factor (NGF) and shows the isolation and purification of this factor.             
              Siigur states that NGF may be isolated from other venoms.    Banks also describes the                     
              isolation of NGF from snake venoms.   Lawman is relied on for the use of NGF to promote                   
              wound healing.                                                                                            
                     The examiner’s position is that, based on the disclosure that NGF accelerates                      
              wound healing and that NGF is found in snake venoms, “it would have been obvious to one                   
              of ordinary skill in the art that the protein isolated from taipoxin can also be reasonably               
              expected to be a growth factor and to accelerate and promote wound healing.”  Answer,                     
              page 6.   It would have also been obvious “to incorporate the factor in an ointment since                 
              this is a conventional expedient [sic, excipient] in medications for wound healing because                
              of its administration to lesions and wounds.”  Id.                                                        
                     At best, the examiner has shown that nerve growth factor has been isolated from the                
              venom of other types of snakes and that nerve growth factor has been found to be useful in                
              the treatment of wounds.  The examiner has not indicated, and we do not find, evidence of                 
              record which shows that any component of the venom from the taipan snake  (Oxyuranus s.                   


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