Ex parte RHODES - Page 3




                   Appeal No.  1997-3019                                                                                                                            
                   Application No. 08/404,122                                                                                                                       

                   Gao et al. (Gao), “An Essential Role for Constitutive Schiff Base-Forming Ligands in                                                             
                   Antigen Presentation to Murine T Cell Clones,” Journal of Immunology, Vol. 144, No. 8, pp.                                                       
                   2883-2890 (April 15, 1990)                                                                                                                       


                                                                       DISCUSSION                                                                                   
                            The claims stand rejected as follows:                                                                                                   
                            I.  Claims 1, 2, 4, 5, 10, and 11 under 35 U.S.C. § 103 as unpatentable over Knop,                                                      
                   Lipkowitz, Rhodes, Gao, Roitt and Ada.                                                                                                           
                            II.  Claim 3, under 35 U.S.C. § 103 as unpatentable over Knop, Lipkowitz, Rhodes,                                                       
                   Gao, Roitt, Ada and the Sigma Catalog.                                                                                                           
                            III.  Claims 6 through 8 under 35 U.S.C. § 103 as unpatentable over Knop,                                                               
                   Lipkowitz, Rhodes, Gao, Roitt, Ada and UK Patent 1,569,003.                                                                                      
                            We reverse all three rejections.  In addition, we raise an issue for the consideration                                                  
                   of the examiner upon return of the application to the examining group.                                                                           
                                                                      BACKGROUND                                                                                    
                            A vaccine, in the context of the claims, and in general, “stimulate[s] a specific                                                       
                   immune response consisting of protective antibodies and T cell immunity,” and upon                                                               
                                                                                                                     2                                              
                   administration to a non-immune individual, “induces active immunity.”   An adjuvant is a                                                         







                            2 Illustrated Dictionary of Immunology, J.M. Cruse and R.E. Lewis, CRC Press, Inc.                                                      
                   Boca Raton, FL, 1995, page 309 (“vaccine”) attached.                                                                                             
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