Ex parte BUSH et al. - Page 7






                 Appeal No. 1997-3511                                                                                                                   
                 Application No. 08/233,663                                                                                                             
                 remains that one obtains a clearer picture of the prior art relative to the claimed invention                                          
                 when one reviews the full text document.                                                                                               
                          In addition, we would note that the translation of German Patent 4,001,451, at page                                           
                 2, would appear to make a distinction between the use of cryoprecipitates of VIII and                                                  
                 solutions of IX.  It is not clear that either the examiner or appellants have considered the                                           
                 relevancy of this information.  What is clear from the present record, however, is that                                                
                 neither the examiner or appellants have had the opportunity to review and consider the                                                 
                 translations of the documents most relevant to the determination of the obviousness of the                                             
                 present claimed invention.  Therefore, we remand this application, with copies of these                                                
                 documents and the translations, to the examiner for full consideration of whether one or                                               
                 both form the proper basis for questioning the patentability of the present claims under 35                                            
                 U.S.C. § 103.  In so doing we offer the following remarks which we hope will be helpful and                                            
                 provide guidance in considering the issues raised by this appeal.                                                                      
                          The examiner has taken the position that the ‘451 abstract describes a composition                                            
                 of the type claimed except for the presence of the buffering agent or the surfactant.                                                  
                 (Answer, page 4).  The examiner offers Wang as teaching that “[i]t is well known in the art                                            
                 that to stabilize proteins the use of stabilizers that prevent denaturation is routine.”  (Id.).                                       
                 The examiner urges that Wang “disclose[s] that of the factors that contribute to                                                       
                 denaturation, pH, detergents or physical stress are some factors that contribute to                                                    


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