Ex parte OHTAKE et al. - Page 4




             Appeal No. 1998-1625                                                                                 
             Application 08/306,517                                                                               


                    A specification complies with the 35 U.S.C. § 112, first                                      
             paragraph, written description requirement if it conveys with                                        




             reasonable clarity to those skilled in the art that, as of the                                       
             filing date sought, the inventor was in possession of the                                            
             claimed                                                                                              
             invention.  See Vas-Cath Inc. v. Mahurkar, 935 F.2d 1555,                                            
             1563-64, 19 USPQ2d 1111, 1117 (Fed. Cir. 1991); In re Kaslow,                                        
             707 F.2d 1366, 1375, 217 USPQ 1089, 1096 (Fed. Cir. 1983); In                                        
             re Edwards, 568 F.2d 1349, 1351-52, 196 USPQ 465, 467 (CCPA                                          
             1978); In re Wertheim, 541 F.2d 257, 262, 191 USPQ 90, 96                                            
             (CCPA 1976).  “[T]he PTO has the initial burden of presenting                                        
             evidence or reasons why persons skilled in the art would not                                         
             recognize in the disclosure a description of the invention                                           
             defined by the claims.”  Wertheim, 541 F.2d at 263, 191 USPQ                                         
             at 97.                                                                                               
                    The examiner argues: “Graft and stem molecules are not                                        
             described adequately enough that it can be clearly                                                   
             distinguished what is meant by graft and stem, and which                                             

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