Appeal No. 1998-1987 Application No. 07/915,783 “[W]hen the PTO shows sound basis for believing that the products of the applicant and the prior art are the same, the applicant has the burden of showing that they are not.” In re Spada, 911 F.2d 705, 708, 15 USPQ2d 1655, 1658 (Fed. Cir. 1990). Appellant has not shown that the prior art compositions fail to meet any of the limitations of claim 68. We therefore affirm the rejections under 35 U.S.C. § 102 based on Kilejian and Epstein. Since we find that Kilejian and Epstein anticipate claim 68, we do not reach the alternative basis under 35 U.S.C. § 103. We also find it unnecessary to consider the disclosures of Schmidt-Ullrich, Howard, and Newbold, which were relied on as alternatives to Kilejian or Epstein. 5. The § 103 rejection. The examiner rejected claims 84-88 and 90-100 as obvious in view of the disclosure of either Kilejian or Schmidt-Ullrich. The examiner reasons that the references teach processes of obtaining plasmodial parasite antigens using non- ionic detergent, and that the process steps recited in the claims “appear to be conventional extraction steps and known to persons of skill in the art at the time the invention was made.” Examiner’s Answer, pages 14-15. Therefore, the examiner concludes that the claimed process would have been obvious in view of the references. “It is well-established that before a conclusion of obviousness may be made based on a combination of references, there must have been a reason, suggestion, or motivation to lead an inventor to combine those references.” Pro- Mold and Tool Co. v. Great Lakes Plastics Inc., 75 F.3d 1568, 1573, 37 USPQ2d 18Page: Previous 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 NextLast modified: November 3, 2007