Ex parte JANOFF et al. - Page 5




              Appeal No. 98-2247                                                                       5               
              Application No. 08/108,822                                                                               

              opposed to the definiteness of the claimed subject matter.                                               

                     However, it is well settled that breadth does not necessarily render a claim                      

              indefinite and the examiner has stated no other ground of rejection.  In re Gardner, 427                 

              F.2d 786, 788, 166 USPQ 138, 140 (CCPA 1970) (“Breadth is not indefiniteness.”);                         

              In re Borkowski, 422 F.2d 904, 909, 164 USPQ 642, 645-46 (CCPA 1970).                                    

              Furthermore, we find that the description in the specification, page 17,                                 

              provides for the addition of a water soluble compound to previously formed liposomes in                  

              at least one disclosed embodiment.  Therefore, liposomes may be prepared in the                          

              absence of a water soluble compound, such as a bioactive agent, which agent is not a                     

              necessary element as alleged on the record before us.  Accordingly, the claimed subject                  

              matter directed to the formation of a liposome in the absence of a water soluble                         

              compound, such as a bioactive agent, is not indefinite                                                   

              On this record, we conclude that the specification provides a reasonable standard                        

              for understanding the metes and bounds of the claimed subject matter, when the claims                    

              are read in light of the specification.  Seattle Box Co. v. Industrial Crating & Packing, Inc,           

              731 F.2d 818, 826, 221 USPQ 568, 573-574 (Fed. Cir. 1983).  Accordingly, we                              

              reverse the rejection of the examiner.                                                                   



              The Rejection under 35 U.S.C. § 103                                                                      

              “[T]he examiner bears the initial burden, on review of the prior art or on any                           






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