Appeal No. 1998-2581 Application No. 08/472,965 establishing a prima facie basis to deny patentability rests with the examiner and the examiner, if relying on a theory of inherency, must provide a basis in fact and/or technical reasoning to reasonably support a determination that the allegedly inherent characteristic necessarily flows from the teachings of the prior art. See In re Oelrich, 666 F.2d 578, 581, 212 USPQ 323, 326 (CCPA 1981). Inherency cannot be established by probabilities or possibilities. See In re Robertson, 169 F.3d 743, 745, 49 USPQ2d 1949, 1951 (Fed. Cir. 1999). The examiner has failed to show by fact and/or reasoning that the insertion of the pipette 34 into the aperture 32 of Zipilivan would have necessarily resulted in a gas-tight or liquid-tight seal with the concentration chamber. Actually, the examiner has not cited any evidence or reasoning that the pipette 34 is even inserted into aperture 32 during the introduction of the liquid sample since Figures 1 and 4 of the reference do not show the pipette 34 in the aperture 32. Of course, the pipette 34 must be inserted into aperture 32 and go through channel 36 for withdrawal of the concentrated liquid sample (see col. 3, ll. 28-30; 40-46). Merely because the sizes 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007