Appeal No. 1998-2581
Application No. 08/472,965
APPENDIX
1. In a device for removing or replacing solvent in a
liquid sample containing macromolecules comprising a
concentration chamber (3) having at least one rigid wall and one
opposite wall formed from a membrane (7) permeable to said
solvent, an aperture adjacent an upper part of said
concentration chamber for introduction and removal of liquid, a
pocket (11) in its lover portion for retaining a fixed volume of
a concentrated sample, and an absorption container (1) provided
with absorbent material (l0) arranged closely adjacent said
membrane wall of said concentration chamber and capable of
absorbing said solvent, the improvement comprising said aperture
adjacent the upper end of said concentration chamber arranged to
receive an outlet of a detachable auxiliary upper reservoir (5),
and means for providing a gas-tight or liquid-tight seal between
said auxiliary reservoir and the concentration chamber when said
auxiliary reservoir is received in said aperture in the
concentration chamber.
2. In a device for removing or replacing solvent in a
liquid sample containing macromolecules comprising a
concentration chamber (3) having at least one rigid wall and one
opposite wall formed of a membrane (7) permeable to said
solvent, an aperture adjacent an upper part of said
concentration chamber for introduction and removal of liquid, a
pocket (11) in its lower portion for retaining a fixed volume of
a concentrated sample, and an absorption container (1) provided
with absorbent material (10) arranged closely adjacent said
membrane wall of said concentration chamber and capable of
absorbing said solvent, the improvement comprising a detachable
auxiliary upper reservoir (5) arranged fixed to said aperture
adjacent the upper end of said concentration chamber and means
for providing a gas-tight or liquid-tight seal between said
auxiliary reservoir and the concentration chamber (3) when said
auxiliary reservoir (5) is received in said aperture in the
concentration chamber (3).
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