Appeal No. 1998-2637 Page 6 Application No. 08/470,142 The test for obviousness is what the combined teachings of the prior art would have suggested to one of ordinary skill in the art. See, for example, In re Keller, 642 F.2d 413, 425, 208 USPQ 871, 881 (CCPA 1981). In establishing a prima facie case of obviousness, it is incumbent upon the examiner to provide a reason why one of ordinary skill in the art would have been led to modify a prior art reference or to combine reference teachings to arrive at the claimed invention. See Ex parte Clapp, 227 USPQ 972, 973 (Bd. Pat. App. & Int. 1985). To this end, the requisite motivation must stem from some teaching, suggestion or inference in the prior art as a whole or from the knowledge generally available to one of ordinary skill in the art and not from the appellants' disclosure. See, for example, Uniroyal, Inc. v. Rudkin-Wiley Corp., 837 F.2d 1044, 1052, 5 USPQ2d 1434, 1439 (Fed. Cir.), cert. denied, 488 U.S. 825 (1988). (2) The first of the rejections under Section 103 is that independent claim 57 and dependent claims 58-60 and 67 are unpatentable over Melker in view of Lee. Claim 57 recites a method comprising a first step of providing a cannula with a sheath at least partially enclosing a plurality of wires “having leading end portions at a leading end portion of the sheath,” engaging a surface area of the side wall of a vessel “with at least a portion of the leading end portion of at least one of the wires and at least a portion of the leadingPage: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007