Ex parte TOWNSEND et al. - Page 5




              Appeal No. 1999-0111                                                                                        
              Application 08/484,593                                                                                      
              4-methyl umbelliferyl galactoside (a galactosidase substrate).  Koumura, the abstract; col.                 
              2, lines 14-44.                                                                                             
                     According to the examiner,                                                                           
                            It would have been obvious to one of ordinary skill in the art at the time the                
                     invention was made to test samples of food and water as shown by Koumura with                        
                     the method of Sussman or Carr because Sussman and Carr teach biological                              
                     samples in general and the method of Koumura is closely related to the methods of                    
                     Sussman and Carr and teaches both foods and water as samples [Answer,                                
                     p. 6].                                                                                               
                     We disagree.                                                                                         
                     It is well established that the examiner has the initial burden under § 103 to                       
              establish a prima facie case of obviousness.  In re Oetiker, 977 F.2d 1443, 1445,                           
              24 USPQ2d 1443, 1444 (Fed. Cir. 1992); In re Piasecki, 745 F.2d 1468, 1471-72,                              
              223 USPQ 785, 787-88 (Fed. Cir. 1984).  It is the examiner’s responsibility to show that                    
              some objective teaching or suggestion in the applied prior art, or knowledge generally                      
              available [in the art] would have led one of ordinary skill in the art to combine the                       
              references to arrive at the claimed invention.  Pro-Mold & Tool Co. v. Great Lakes Plastics,                
              Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629 (Fed. Cir. 1996).  This the examiner                         
              has not done.                                                                                               
                     Here, we find that the rejection fails because the examiner has not come to grips                    
              with the fact that all of the claims, i.e., both the claims to the methods and to the bacterial             
              growth medium, require the presence of a specific combination of enzyme substrates in                       
              said growth medium.  Thus, the burden is on the examiner to demonstrate                                     

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