Appeal No. 1999-0111 Application 08/484,593 4-methyl umbelliferyl galactoside (a galactosidase substrate). Koumura, the abstract; col. 2, lines 14-44. According to the examiner, It would have been obvious to one of ordinary skill in the art at the time the invention was made to test samples of food and water as shown by Koumura with the method of Sussman or Carr because Sussman and Carr teach biological samples in general and the method of Koumura is closely related to the methods of Sussman and Carr and teaches both foods and water as samples [Answer, p. 6]. We disagree. It is well established that the examiner has the initial burden under § 103 to establish a prima facie case of obviousness. In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed. Cir. 1992); In re Piasecki, 745 F.2d 1468, 1471-72, 223 USPQ 785, 787-88 (Fed. Cir. 1984). It is the examiner’s responsibility to show that some objective teaching or suggestion in the applied prior art, or knowledge generally available [in the art] would have led one of ordinary skill in the art to combine the references to arrive at the claimed invention. Pro-Mold & Tool Co. v. Great Lakes Plastics, Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629 (Fed. Cir. 1996). This the examiner has not done. Here, we find that the rejection fails because the examiner has not come to grips with the fact that all of the claims, i.e., both the claims to the methods and to the bacterial growth medium, require the presence of a specific combination of enzyme substrates in said growth medium. Thus, the burden is on the examiner to demonstrate 5Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007