Ex parte EWASYSHYN et al. - Page 2




                   Appeal No. 1999-1162                                                                                                                             
                   Application No. 08/427,837                                                                                                                       



                            Claims 9, 19 and 20 are the claims on appeal and read as follow:                                                                        
                               1                                                                                                                                    
                            9.        A composition, comprising a protective, highly-immunogenic, non-                                                              
                   immunopotentiating copurified mixture of HN and F glycoproteins of human parainfluenza                                                           
                   type 3 prepared by copurification from native PIV-3 virus by affinity chromatography.                                                            
                            19.       The composition of claim 9 for human administration containing alum as                                                        
                   (aluminum phosphate) an adjuvant.                                                                                                                
                            20.       The composition of claim 19 formulated for administration by injection.                                                       

                   The prior art references relied upon by the examiner are:                                                                                        
                   Wathen                                                    5,284,764                             Feb.  8, 1994                                    
                   Ray et al. (Ray), “Role of Individual Glycoproteins of Human Parainfluenza Virus Type 3 in                                                       
                   the Induction of a Protective Immune Response,” Journal of Virology, Vol. 62, No. 3, pp.                                                         
                   783-787 (1988).                                                                                                                                  
                                                                           OPINION                                                                                  
                            In reaching our decision in this appeal, we have given careful consideration to the                                                     
                   appellants’ specification and claims, to the applied prior art references, and to the                                                            
                   respective positions articulated by the appellants and the examiner.                                                                             

                            1This claim is reproduced as it appears in the amendment filed October 30, 1996.                                                        
                   We note that this amendment to claim 9 has not been properly entered, since claim 9 of                                                           
                   the amendment filed December 18, 1995 is still present in the case.  Upon return of this                                                         
                   application to the examining group we would urge the examiner to review the amendment                                                            
                   filed October 30, 1996 to ascertain whether it is in compliance with                                                                             
                   37 C.F.R. 1.121(a)(2).   For example, we note that a comma has been deleted after                                                                
                   “protective” in line 2, and that the text “(PIV-3)" is no longer present after “type 3".   Yet,                                                  
                   these changes are not indicated as changes in the amendment of October 30, 1996.   We                                                            
                   have considered the issues raised by this appeal as they relate to the claim 9 reproduced                                                        
                   above.                                                                                                                                           
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