Ex Parte SIMS et al - Page 2


                 Appeal No.  1999-1430                                                                                
                 Application No.  08/441,893                                                                          

                        Claim 161 is illustrative of the subject matter on appeal and is reproduced                   
                 below:                                                                                               
                        16. An isolated and purified Type II IL-1 receptor (Type II IL-1R) that                       
                            binds IL-1, and is encoded by a DNA that hybridizes under                                 
                            moderately stringent conditions with a DNA selected from the group                        
                            consisting of:                                                                            
                               (a) a DNA encoding a Type II IL-1R having an amino acid                                
                                  sequence as set forth in SEQ ID NO.:2, having an amino                              
                                  terminus at amino acid 1, and a carboxy terminus selected from                      
                                  the group consisting of an amino acid between amino acids 330                       
                                  and 385, inclusive, of SEQ ID NO.:2;                                                
                               (b) a DNA encoding a Type II IL-1R having an amino acid sequene                        
                                  as set forth in SEQ ID NO.:13, having an amino terminus at                          
                                  amino acid 1, and a carboxy terminus selected from the group                        
                                  consisting of an amino acid between amino acids 342 and 397,                        
                                  inclusive, of SEQ ID NO.:13; and                                                    
                               (c) a DNA encoding a fragment of the polypeptide of (a) or (b),                        
                                  which fragment binds IL-1.                                                          
                        References relied upon by the examiner2.                                                      
                 Sims et al. (Sims)                 5,464,937                        Nov. 7, 1995                    













                                                                                                                      
                 1 We note the examiner’s notation (Answer, page 3) of errors present in                              
                 appellants’ Brief, Appendix A, Claims on Appeal.  Claim 16 is correctly                              
                 reproduced herein.                                                                                   
                 2 We note the examiner incorrectly states (Answer, page 3) that “[n]o prior art is                   
                 relied upon by the examiner in the rejection of the claims under appeal.”                            

                                                          2                                                           



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