Ex parte JONAS et al. - Page 3





              Appeal No. 1999-1681                                                                                       
              Application 08/634,830                                                                                     


                                                 THE REFERENCES                                                          


                     The prior art references relied on by the examiner are:                                             
              Yamamoto et al. (Yamamoto)                       3,682,914                  Aug 8, 1972                  
              Hakim et al. (Hakim)                             3,975,388                  Aug 17, 1976                 
              Sircar (Sicar '854)                              4,397,854                  Aug 9, 1983                  
              Sicar et al. (Sicar et al. '415)                 4,734,415                  Mar 29, 1988                 
              Burger, Alfred (editor), Medicinal Chemistry, Second Edition, Interscience Publishers, Inc.,               
              New York, page 43 (1960)                                                                                   

                                                  THE REJECTIONS                                                         


                     The appealed claims stand rejected as follows:                                                      
              (1)    Claims 1, 2, 5, 6, and 12 through 16 under 35 U.S.C. § 103(a) as unpatentable over                  
              the combined disclosures of Sicar '854 and Burger;                                                         
              (2)    Claims 1, 2, 5, 6, and 12 through 16 under 35 U.S.C. § 103(a) as unpatentable over                  
              the combined disclosures of Hakim, Sicar '854, Sicar et al '415, and Burger;                               
              (3)    Claims 1, 2, 5, 6 and 12 under 35 U.S.C. § 103(a) as unpatentable over the                          
              combined disclosures of Yamamoto and Burger;                                                               
              (4)    Claim 5 under 35 U.S.C. § 103 as "the obvious method of making a mixture and                        
              therefore unpatentable" (Examiner's Answer, page 12); and                                                  




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