Appeal No. 1999-1730 Application No. 08/478,205 dissertation to be important. Only with the benefit of hindsight can this passage be read to suggest mutating other amino acids in the 223-247 region. We therefore agree with Appellants that the cited references would not have motivated a person of ordinary skill in the art to alter the amino acid sequence of P. plagiophthalamus luciferase at the positions recited in claim 1. Since the references do not provide the requisite motivation to make the claimed product, they do not support a prima facie case of obviousness. Summary We reverse the rejection for obviousness because the cited reference do not provide the requisite motivation to modify the known compound as required to meet the limitations of the claims. REVERSED Douglas W. Robinson ) Administrative Patent Judge ) ) ) ) BOARD OF PATENT Donald E. Adams ) Administrative Patent Judge ) APPEALS AND ) ) INTERFERENCES ) Eric Grimes ) Administrative Patent Judge ) EG/dym 8Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007