Ex parte SUTTON et al. - Page 2




               Appeal No. 1999-1731                                                                                              
               Application 08/411,815                                                                                            

                                                    Representative Claims                                                        
                      Claims 24 and 46, which are illustrative of the subject matter on appeal, read as                          
               follows:                                                                                                          
                      24.  A process of preparing microcapsules, the process comprising the steps of:                            
                      (i)  spray-drying a solution or dispersion of at least one wall-forming material in a                      
                      liquid carrier into a gas in order to obtain gas- or vapor-filled microcapsules by                         
                      evaporation of said liquid carrier, and                                                                    
                      (ii)  including at least one charge-altering material in or on said microcapsules to                       
                      adapt said microcapsules for selective targeting to an area of a human or animal                           
                      body.  [Emphasis added.]                                                                                   

                      46.  A method for generating an ultrasound image of a region of a human or animal                          
               body comprising the steps of:                                                                                     
                      (i)  introducing to said region an ultrasound contrast agent formed by                                     

                              (1)  spray drying a solution or dispersion of at least one wall-forming material                   
                              in a liquid carrier into a gas to obtain gas- or vapor-filled microcapsules by                     
                              evaporation of said liquid carrier; and                                                            
                              (2)  including at least one charge-altering material in or on said                                 
                              microcapsules to adapt said microcapsules for selective targeting to an                            
                              area of a human or animal body;                                                                    
                      (ii)  exposing said ultrasound contrast agent to ultrasonic energy; and                                    
                      (iii)  creating an image from the reflection of the ultrasonic energy by said ultrasound                   
                      contrast agent;                                                                                            
               wherein said microcapsules selectively target the region of the human or animal body to be                        
               imaged.  [Emphasis added.]                                                                                        



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