compound had pharmacologically useful anti-inflammatory
activity.
(2) Anderson points to two pages of results he testified
he recorded in his notebook (Exh. 2051) for SC-60668 and
various other compounds that we assume are not within the
scope of the count. However, we cannot be sure of the exact
make up of the other compounds since we are not told. We
cannot be sure of the significance of the figures for
percentage inhibition for each tested compound since the
formula used to obtain the figures is not adequately explained
(e.g., the meaning of "ave. paw vol. Vehicle" is not
explained). We note that some of the compounds yield a higher
percentage of inhibition than does
SC-60668 at either .3 or 2 mpk (e.g., 60583 at 3 mpk and Indo
at .2 mpk). We also note that SC-60668 at .3 mpk yields a 4
percent inhibition while at 2 mpk the compound yields a 42%
inhibition. However, we have not been provided with adequate
testimony explaining the significance of the performance of
SC-60668 relative to the other compounds tested or the
significance of the dose of SC-60668 required to achieve 41
percent inhibition (e.g., is the dose pharmacologically
practical?).
37
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