Ex Parte LAZARUS - Page 7




                    Appeal No. 2000-1759                                                                                                                                  
                    Application No. 08/748,637                                                                                                                            


                    Like appellant, we find that, in the relevant time frame                                                                                              
                    (circa 1983), a person of ordinary skill in the art would not                                                                                         
                    have looked to the invasive, aortic surgical repair method of                                                                                         
                    Kononov and a device like that of Kononov, wherein the device is                                                                                      
                    sized to be inserted directly into an opening formed in the aorta                                                                                     
                    itself, to modify a minimally-invasive repair method like that in                                                                                     
                    Choudhury where the repair device is inserted at a location                                                                                           
                    remote from the aorta, such as the smaller femoral artery in a                                                                                        
                    patient's leg, and then fed through the patient's vasculature to                                                                                      
                    the point in the aorta where repair is needed.  In that regard,                                                                                       
                    we note that the examiner has essentially provided no response to                                                                                     
                    the evidence and arguments presented by appellant in the                                                                                              
                    declarations by Dr. Thoshinsky and the brief and reply brief.                                                                                         
                    More specifically, the declarations by Dr. Thoshinsky, who                                                                                            
                    practiced in the field of vascular surgery for 38 years and                                                                                           
                    during the relevant time frame of 1979 through 1983, set forth                                                                                        
                    numerous reasons why one of ordinary skill in the art at the time                                                                                     
                    of appellant's invention would have found no motivation in the                                                                                        
                    references applied by the examiner for making the combination                                                                                         
                    urged in the rejection on appeal, and instead would have found                                                                                        
                    many disincentives in those references for attempting to make                                                                                         
                    such a combination.  In the face of appellant's evidence setting                                                                                      

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