Ex Parte VERMA et al - Page 9


                 Appeal No.  2000-1930                                                       Page 9                   
                 Application No.  08/232,452                                                                          

                        As noted above, the examiner never separately addressed the                                   
                 patentability of the product of claim 29.  Upon return of the application, the                       
                 examiner may wish to consider the patentability of the product separately from                       
                 the method of use.  The combination of Palmer or Anson with Bell suggests the                        
                 use of a full-thickness skin equivalent to introduce genetically modified                            
                 fibroblasts, and one of the intermediates would possibly be the collagen matrix of                   
                 Bell combined with the genetically modified fibroblasts of Palmer or Anson or                        
                 one of the other references cited by the examiner.  But as this is not the rejection                 
                 of record, and as appellants have not had the opportunity to address the issue of                    
                 a possible intermediate with respect to the product claim, we are raising the                        
                 issue here, and not affirming the rejection over the combination as to the product                   
                 of claim 29.                                                                                         

























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