Ex Parte PENNINI et al - Page 8


          Appeal No. 2001-0968                                                       
          Application No. 08/894,423                                                 

          based on inherency under 35 U.S.C. § 102 or on obviousness under           
          35 U.S.C. § 103, jointly or alternatively, the burden of proof is          
          the same, and its fairness is evidenced by the PTO's inability to          
          manufacture products or to obtain and compare prior art products.          
          Best, 562 F.2d at 1255, 195 USPQ at 433-34.                                
               Although Dietz's Catalyst 4 is made by using n-hexane, as             
          distinguished from an aromatic hydrocarbon or a halogenated                
          hydrocarbon as recited in appealed claim 1, we again point out             
          that the appealed claims do not require the contact of the                 
          titanium compound with the specified organic solvent, i.e. the             
          aromatic hydrocarbon or halogenated hydrocarbon.  Also, nothing            
          in the record, including the experimental data in the present              
          specification, establishes that the use of an aromatic or                  
          halogenated hydrocarbon yields a substantially different                   
          catalyst, much less any unexpected result, relative to the use of          
          n-hexane.                                                                  
               Even assuming that the use of the recited solvents imparts a          
          structural difference relative to n-hexane, Dietz teaches the use          
          of an aromatic hydrocarbon (e.g., benzene or toluene) as the               
          solvent.  Under these circumstances, one of ordinary skill in the          
          art would have found it prima facie obvious to replace the n-              
          hexane of Example 1 with benzene or toluene, with the reasonable           
          expectation that these solvents would provide substantially                
          similar results relative to n-hexane as expressly taught by                
          Dietz.  In re Longi, 759 F.2d 887, 897, 225 USPQ 645, 651-52               
          (Fed. Cir. 1985)(holding that the use of nitrogen-containing               
          titanium compounds in a Ziegler-Natta catalyst in lieu of other            
          titanium compounds would have been prima facie obvious to one of           
          ordinary skill in the art); In re Mayne, 104 F.3d 1339, 1342-43,           
          41 USPQ2d 1451, 1454-55 (Fed. Cir. 1997)(holding that the                  
          substitution of a peptide for another functionally equivalent              
          peptide in recombinant DNA art would have been prima facie                 
          obvious to one of ordinary skill in the art).                              
               As to the amount of alcohol, Dietz teaches that the amount            
          of alcohol may be as little as 2 moles per more of magnesium               
          dichloride.  Accordingly, we determine that one of ordinary skill          
          in the art would have found it prima facie obvious to use an               
          amount as low as 2 moles of alcohol per mole of magnesium                  
          dichloride, as expressly suggested in the reference.  In re                
          Geisler, 116 F.3d 1465, 1469, 43 USPQ2d 1362, 1365 (Fed. Cir.              
          1997)(explaining that a claimed invention is rendered prima facie          
          obvious when the teachings of a prior art reference discloses a            
          range that touches or overlaps the range recited in the claim).            
               Claim 2 recites the presence of "up to 15 mmoles" of                  
          "chemically not combined water" per gram of metal oxide.  We hold          
          that the recitation "up to 15 mmoles" reads on 0 mmole.  Even if           
          a positive amount up to 15 mmoles had been recited, we determine           
          that the use of commercially available silicas in Dietz would              
          meet this limitation for the reasons discussed above with respect          


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