Ex Parte SOLTERO et al - Page 2


                 Appeal No.  2001-1524                                                        Page 2                   
                 Application No.  08/615,058                                                                           
                        The references relied upon by the examiner are:                                                
                 Tye                              4,529,719                  Jul.   16, 1985                        
                 Fischer et al. (Fischer)           5,428,007                  Jun.  27, 1995                         
                 Kramer et al. (Kramer)             5,443,848                  Aug. 22, 1995                          
                 Nguyen et al. (Nguyen), “Current Treatment of Severely Burned Patients,”                              
                 Annals of Surgery, Vol. 223, No. 1, pp. 14-25 (1996)                                                  
                        The references relied upon by appellants are:                                                  
                 Przybelski                        5,334,706                  Aug. 2, 1994                           
                 Sharma et al. (Sharma), “Regional Circulatory and Systemic Hemodynamic                                
                 Effects of Diaspirin Cross-linked Hemoglobin in the Rat,” Art. Cells, Blood Subs.,                    
                 and Immob. Biotech., Vol. 22, No. 3, pp. 593-602 (1994)                                               
                                            GROUNDS OF REJECTION                                                       
                        Claims 6, 7 and 9 stand rejected under 35 U.S.C. § 103 as being                                
                 unpatentable over Kramer in view of Fischer.                                                          
                        Claims 6-8 and 10 stand rejected under 35 U.S.C. § 103 as being                                
                 unpatentable over Kramer in view of Fischer, further in view of Nguyen.                               
                        Claims 11 and 12 stand rejected under 35 U.S.C. § 103 as being                                 
                 unpatentable over Kramer in view of Fischer and Tye.                                                  
                        Claims 11-14 stand rejected under 35 U.S.C. § 103 as being unpatentable                        
                 over Kramer in view of Fischer and Tye, further in view of Nguyen.                                    
                        We reverse.                                                                                    
                                                    DISCUSSION                                                         
                        According to the examiner (Answer, page 3), “Kramer teaches a method                           
                 of overcoming circulatory shock due inter alia to burns characterized by                              
                 increasing cardiac output….”  The examiner finds (id.), “[a] ‘particularly useful’                    
                 embodiment of the method of Kramer is the inclusion of stroma-free hemoglobin,                        





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