Ex Parte KLEIN et al - Page 4


                 Appeal No. 2001-1587                                                                                     
                 Application No. 08/506,268                                                                               

                         less handling steps and the result can be determined in a very rapid                             
                         and simple manner.                                                                               
                         Appellants’ Brief emphasizes that the claims include the limitation of                           
                 maintaining contact between the wiping surface and test strip during the assay                           
                 procedure.  See pages 3-4:  “The key point is that the wiping surface must                               
                 remain in contact with the contact site while the liquid eluant passes through the                       
                 contact site . . . in order to increase the amount of analyte carried downstream for                     
                 immunoassay, so that the method of the present invention is simple and yet more                          
                 sensitive than prior art methods” (emphasis in original).                                                
                                                       Discussion                                                         
                         The examiner rejected all of the claims as obvious over Fitzpatrick, Giegel,                     
                 and Baier.  The examiner characterized Fitzpatrick as “teach[ing] a device . . .                         
                 and an assay . . . for detecting the presence of an analyte in a sample.  The                            
                 device contains a capillary active, chromatographic test strip having a planar                           
                 surface and two ends, with an eluant application zone proximate one end and a                            
                 target zone (detection zone) proximate the other end, with a capture zone (trap                          
                 zone) in between.”  Examiner’s Answer, page 4.  According to the examiner,                               
                 Fitzpatrick differs from the present claims only in that it “does not teach a wiping                     
                 surface for collection of analyte nor conducting the contact of the test strip                           
                 surface with the wiping surface with the aid of a contact pressure device.”  Id.  He                     
                 relies on Giegel and Baier to make up these differences, citing Giegel as                                
                 “teach[ing] a swab device for collecting a sample from a surface,” and Baier as                          
                 “teach[ing] a carrier fleece containing cellulose and/or polyester.”  Id.                                


                                                            4                                                             



Page:  Previous  1  2  3  4  5  6  7  8  Next 

Last modified: November 3, 2007