Ex Parte TAKLE et al - Page 5


                 Appeal No.  2001-1705                                                       Page 5                  
                 Application No.  08/616,141                                                                         
                 not met her burden on this record.  Accordingly, we reverse the rejection of claim                  
                 31 under 35 U.S.C. § 112, first paragraph.                                                          
                 THE REJECTION UNDER 35 U.S.C. § 102:                                                                
                        The following quote represents the examiner’s entire statement of                            
                 rejection under 35 U.S.C. § 102(b).  “Claims 1, 2, 5, 6, 19, 20, 23, and 30 stand                   
                 rejected under 35 U.S.C. [§] 102(b) as being anticipated by Cannon.”  Answer,                       
                 page 5.  In responding to appellants’ arguments (Answer, page 8), the examiner                      
                 finds:                                                                                              
                        [t]he instant claims are drawn to compositions comprising a                                  
                        compound having a net negative charge ionically bound to a                                   
                        macrocycle (porphyrin) having a net positive charge and to                                   
                        methods of delivering compounds having a net negative charge to                              
                        cells comprising mixing the compound with a macrocycle having a                              
                        net positive charge, wherein the macrocycle ionically binds to the                           
                        compound.                                                                                    
                        Conspicuous in its absence in this statement, and the statement of the                       
                 rejection, is any explanation as to why the amounts in Cannon would be effective                    
                 to enhance delivery of the compound to cells that bind the macrocycle, as is                        
                 required by the claimed invention.  While the examiner argues (Answer, page 9),                     
                 “[t]he method of Cannon has the same active steps as the claimed method i.e.                        
                 the mixing together of a negatively charged compound (lipid) with a positively                      
                 charged macrocycle … and the delivery of the mixture to cells” the examiner fails                   
                 to explain where Cannon teaches an amount that is effective to enhance delivery                     
                 of the compound to cells as is required by the claimed invention.                                   
                        “Under 35 U.S.C. § 102, every limitation of a claim must identically appear                  
                 in a single prior art reference for it to anticipate the claim.”  Gechter v. Davidson,              







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