Ex Parte SETTERSTROM et al - Page 5


             Appeal No. 2001-1733                                                           Page 5               
             Application No. 09/055,505                                                                              
             considered in judging the patentability of that claim against the prior art.”  In re Wilson,            
             424 F.2d 1382, 1385, 165 USPQ 494, 496 (CCPA 1970).                                                     
                    However, we note the examiner’s statement (Supplemental Examiner’s Answer,                       
             page 2), “[t]he particles formed by the Ramstack et al[.] reference could have a capped                 
             and uncapped end since butyl alcohol would supply the butyl group as previously urged                   
             by the applicant” [emphasis added].  In this regard, we note that Ramstack may just as                  
             well not have an end-capped and uncapped end.  The examiner bears the initial burden                    
             of presenting a prima facie case of obviousness.  In re Oetiker, 977 F.2d 1443, 1445, 24                
             USPQ2d 1443, 1444 (Fed. Cir. 1992).  Stated differently, the examiner has the initial                   
             duty of supplying the factual basis for his rejection.  He may not, because he may doubt                
             that the invention is patentable, resort to speculation, unfounded assumptions or                       
             hindsight reconstruction to supply deficiencies in its factual basis.  See  In re Warner,               
             379 F.2d 1011, 1017, 154 USPQ 173, 178 (CCPA 1967).  Accordingly, in the event of                       
             further prosecution, we encourage the examiner to ensure that his position is clearly                   
             supported by the prior art relied upon.                                                                 
                    Also absent in the Examiner’s Answer is any discussion of how he construed the                   
             claimed invention.  For example, as set forth in claim 1, the composition “may contain” a               
             pharmaceutically-acceptable adjuvant.  Does this mean that a pharmaceutically-                          
             acceptable adjuvant is not a required component of the composition?  If so, then it                     
             seems reasonable that the composition comprises only an active material and a carrier.                  
             We remind the examiner, as set forth in In re Zletz, 893 F.2d 319, 321-22,                              
             13 USPQ2d 1320, 1322 (Fed. Cir. 1989):                                                                  
                    [D]uring patent prosecution when claims can be amended, ambiguities                              
                    should be recognized, scope and breadth of language explored, and                                






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