Ex Parte SANTOLI et al - Page 3


                  Appeal No. 2001-2411                                                                                         
                  Application No. 08/879,422                                                                                   

                  to a mammalian patient in the absence of an immunosuppressive agent.”  Id.,                                  
                  pages 2-3.                                                                                                   
                                                         Discussion                                                            
                          The examiner rejected all of the claims for indefiniteness, inadequate                               
                  written description, and nonenablement.  Each of the rejections is based on the                              
                  same claim limitation: the limitation that the TALL-104 cells are administered to a                          
                  cancer patient “with a functional immune system.”  In the examiner’s view, this                              
                  limitation renders the claims indefinite, inadequately described, and nonenabled.                            
                  We disagree.                                                                                                 
                  1.  Claim construction                                                                                       
                          Claim language must be interpreted in light of the claim as a whole, the                             
                  specification of which the claim is a part, and the prosecution history.  See                                
                  General Foods Corp. v. Studiengesellschaft Kohle mbH, 972 F.2d 1272, 1275,                                   
                  23 USPQ2d 1839, 1840 (Fed. Cir. 1992) (“[E]ach claim is an entity which must                                 
                  be considered as a whole.”) (emphasis in original); Renishaw plc v. Marposs                                  
                  Societa per Azioni, 158 F.3d 1243, 1248, 48 USPQ2d 1117, 1120 (Fed. Cir.                                     
                  1998) (“[A] claim must be read in view of the specification of which it is a part.”);                        
                  id. at 1249 n.3, 48 USPQ2d 1117, 1121 n.3 (“Likewise, any interpretation that is                             
                  provided or disavowed in the prosecution history also shapes the claim scope.”).                             
                          In addition, “[i]t is axiomatic that, in proceedings before the PTO, claims in                       
                  an application are to be given their broadest reasonable interpretation consistent                           
                  with the specification and that claim language should be read in light of the                                
                  specification as it would be interpreted by one of ordinary skill in the art.”                               

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