Ex Parte CHANG - Page 1




                              The opinion in support of the decision being entered today was not written                          
                                      for publication and is not binding precedent of the Board.                                  
                                                                                               Paper No. 34                       
                           UNITED STATES PATENT AND TRADEMARK OFFICE                                                              
                                                         __________                                                               
                                 BEFORE THE BOARD OF PATENT APPEALS                                                               
                                                 AND INTERFERENCES                                                                
                                                         __________                                                               
                                                 Ex parte TSE WEN CHANG                                                           
                                                         __________                                                               
                                                    Appeal No. 2001-2497                                                          
                                                 Application No. 08/855,744                                                       
                                                         __________                                                               
                                                          ON BRIEF                                                                
                                                         __________                                                               
                   Before WILLIAM F. SMITH, SCHENER, and GRIMES, Administrative Patent                                            
                   Judges.                                                                                                        
                   GRIMES, Administrative Patent Judge.                                                                           

                                                   DECISION ON APPEAL                                                             
                          This is a decision on appeal under 35 U.S.C. § 134 from the examiner’s                                  
                   final rejection of claims 1 and 3, all of the claims in the application.  Claim 1 and 3                        
                   read as follows:                                                                                               
                          1.      A method of enhancing delivery of a therapeutic agent selected                                  
                                  from the group consisting of tumor necrosis factor and interleukin-1                            
                                  to a solid tissue site, comprising:                                                             
                                  administering to a patient a conjugate consisting of two individual                             
                                  single chain VH-VL binding molecules which are conjugated with a                                
                                  hydrophilic peptide linker, one single chain binding molecule having                            
                                  specificity for a solid tissue antigen and the other for the therapeutic                        
                                  agent, and waiting until the conjugate concentration in the                                     







Page:  1  2  3  4  5  6  7  8  9  10  11  12  13  Next 

Last modified: November 3, 2007