BELLEAU et al. V. CHENG et al. - Page 6





                                                                                            Interference No. 104,396                    
                                                                                                               Page 6                   
               invention so long as the named elements, which are essential, are included. Genentech, Inc. v.                           
               Chiron Corp., 112 F.3d 495, 501, 42 USPQ2d 1608, 1613 (Fed. Cir. 1997). It is understood,                                

               however, that the open-ended transition "comprising" does not free a claim from its own                                  
               limitations. Specifically, the use of the transition term "comprising" cannot restore subject                            
               matter that is otherwise excluded from the claim. Kustom Signals Inc. v. Applied Concepts, Inc.,                         
               264 F.3d 1326, 1332, 60 USPQ2d 1135, 1139 (Fed. Cir. 2001); Spectrum Intl, Inc. v. Sterilite                             
               Corp., 164 F.3d 1372, 1379-80, 49 USPQ2d 1065, 1070 (Fed. Cir. 1998). As we have construed                               
               the term "(-)-enantiomer" to include, at most, no more than 5 weight percent of the                                      
               enantionter, the term comprising cannot open a claim to the (-)-enantiomer to the inclusion of                           
               more than 5 weight percent of the (+)-enantiomer .4                                                                      

                       We note that a claim directed towards an "admixture" of the (-)-enantiomer and the (+)                           
               enantiomer allows for the presence of major amounts of either the (-) or the (+)-enantiomer.                             
               Specifically, such a claim merely requires that the two components, i.e., the (-) and (+)                                
               enantiomer, both be present. For example, a claim to an "admixture" of the (-)-enantiomer and                            
               the (+)-enantiomer could have 20% of the (-)-enantiomer (which is defined in this interference to                        
               contain at most 5% of the corresponding (+)-enantiomer) and 80% of the (+)-enantiorner. The                              



                       'We note that Belleau claim 4 is directed to a method employing a compound of formula                            
               (1), wherein the compound of formula (1) "comprises" the (-)-enantiomer. Belleau claim 5                                 
               depends from Belleau claim 4 and states that the compound of formula (1) "is substantially free                          
               of the corresponding (+)-enantiomer." It is unclear on this record whether the doctrine of claim                         
               differentiation would require Belleau claim 4 to not be substantially free of the corresponding                          
               (+)-enantiomer. As the parties did not address this issue and as it is not clear that the doctrine of                    
               claim differentiation applies, we maintain our holding that the terminology "comprising (+                               
               enantiomer" allows for no more than 5 weight percent of the corresponding (+)-enantiomer.                                








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