Ex Parte AVERBACK - Page 4


              Appeal No. 1999-0494                                                                                       
              Application 08/482,768                                                                                     

              compounds are suitable for use in the treatment method of the present invention.                           
              Specification, page 32.                                                                                    
                                                     DISCUSSION                                                          
              1.     Rejection under 35 U.S.C. § 112, fourth paragraph                                                   
                     The examiner's reasoning in support of this rejection is:                                           
                     The claims relate to the intended use of the composition.  Therefore, they are not                  
                     a proper definition of the composition as they are not limiting of the composition                  
                     per se.                                                                                             
              Examiner's Answer, page 3.                                                                                 
                     The examiner's statement of the rejection is all but incomprehensible and lacks                     
              logic.  First, it is not clear why claim 13, an independent claim, is subject to this                      
              rejection.  Nor is it clear why claim 15 is subject to this rejection as that claim is limited             
              to a Markush group of specific compounds useful in the composition of claim 13.                            
                     It appears that the examiner's concern in terms of proper dependency is limited                     
              to claim 14.  But neither statement by the examiner explains why claim 14 does not                         
              serve to further limit claim 13.  On its face, claim 14 is directed to a narrower subgenus                 
              of compounds than those required by claim 13 in that the compounds of claim 14,                            
              besides possessing the property required by claim 13, must also inhibit formation of                       
              amyloid fibrils by the activity described in claim 14.                                                     
                     While not clear from the statement of the rejection, it may be the examiner's                       
              concern that not all of the compounds described by appellant in the specification                          
              possess the properties required by both claims 13 and 14.  In other words, appellant                       
              may not have described in the specification compounds possessing the property of                           
              claim 13 but not the property of claim 14.  If so, those question would be properly raised                 

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