Appeal No. 1999-0494 Application 08/482,768 pharmaceutical to retard oxidation." The record copy of the Merck Index is difficult to read due to the photocopy supplied by the examiner but it does not appear to use the word "pharmaceutical." In any event, the examiner's statement of the rejection under 35 U.S.C. § 103(a) is fundamentally deficient in that it does not address the subject matter of the claims as a whole. As seen from claim 13, the composition must be "capable of crossing the blood-brain barrier." Nowhere in the Examiner's Answer does the examiner explain how any of the references relied upon teaches or suggests this aspect of the claimed subject matter. The examiner's rejection under 35 U.S.C. § 103(a) is reversed. NEW GROUND OF REJECTION UNDER 37 CFR § 1.196(b) Under the provisions of 37 CFR § 1.196(b), we make the following new ground of rejection. Claims 13-15 and 17-21 are rejected under 35 U.S.C. § 102(b). As evidence of anticipation, we rely upon Johnson. 1. Claims 13-15 For ease of explaining the facts and reasoning in support of the new ground of rejection, we will consider these three claims as a group. In considering claims 13, 14 and 15 together, it is apparent that cromolyn sodium meets the functional requirements of both claims 13 and 14 in terms of inhibiting formation of amyloid fibrils as confirmed by the results of Example 2 of the present specification. 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007