Ex parte HEITFELD et al. - Page 5


                 Appeal No.  1999-1276                                                          Page 5                    
                 Application No.  08/318,574                                                                              

                 F.3d 1339, 1343, 48 USPQ2d 1635, 1637 (Fed. Cir. 1998).  The mere fact that the                          
                 prior art could be modified to obtain the claimed process does not make the                              
                 modification obvious unless the prior art suggested the desirability of the                              
                 modification.  In re Gordon, 733 F.2d 900, 902, 221 USPQ 1125, 1127 (Fed. Cir.                           
                 1984).  Something in the prior art as a whole must suggest the desirability and thus                     
                 the obviousness of making the combination.  Lindemann Maschinenfabrik GmbH v.                            
                 American Hoist and Derrick Co., 730 F.2d 1452, 1462, 221 USPQ 481, 488 (Fed.                             
                 Cir. 1984).                                                                                              
                         Examiner has established that the references disclose various elements of                        
                 the claimed invention but has not pointed to anything in these references, and we                        
                 can find none, that suggest the desirability of modifying Johnson’s idiometric                           
                 method of quantitating organic peracids to replace the chemical reagents used                            
                 therein to remove hydrogen peroxide with the catalase of the secondary prior art.                        
                         Johnson is, like the claimed method, directed to a method of quantitating                        
                 organic peracids, albeit an idiometric method involving chemical reagents and not                        
                 catalase.  Heath and Bittner use catalase to remove hydrogen peroxide but do not                         
                 quantitate organic peracids; instead, they quantitate hydroperoxides and uricase,                        
                 respectively.  Furthermore, and in contrast to the claimed invention which introduces                    
                 the catalase to a solution of organic peracids and a high background of hydrogen                         
                 peroxide, Heath uses the catalase separately from the actual assay to initially                          
                 incubate the sample to remove hydrogen peroxide (see sentence bridging pp. 185-                          
                 186) and Bittner uses catalase to remove hydrogen peroxide generated as a by-                            






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