Ex Parte SHEPARD et al - Page 5




                     Appeal No. 1999-1433                                                                                                                                              
                     Application 08/453,852                                                                                                                                            
                                                                                  Discussion                                                                                           
                     I.         The double patenting rejection                                                                                                                         
                                The examiner has rejected claims 1, 2, 4, 5 and 14 under the judicially-created                                                                        
                     doctrine of obviousness-type double patenting.  The examiner argues that the present                                                                              
                     claims, which are directed to enhancing an immune response to any non-tumor antigen                                                                               
                     using tumor necrosis factor (TNF), would have been obvious to one of ordinary skill in                                                                            
                     the art in view of claims 1-5 and 8 of U.S. Patent 4,963,354 which describe a method of                                                                           
                     enhancing an immune response to a tumor antigen using TNF.  Answer, p. 4.                                                                                         
                                In response, the appellants do not contest the examiner’s rejection.  Rather, they                                                                     
                     simply state that they will file a terminal disclaimer once there is an indication of                                                                             
                     allowable subject matter.  Brief, p. 17.  However, an intention to file a terminal                                                                                
                     disclaimer is not sufficient to overcome the rejection.  Accordingly, Rejection I is                                                                              
                     affirmed.                                                                                                                                                         
                     II.        The 35 U.S.C.  § 112, first paragraph, rejections                                                                                                      
                                A.         Written description/new matter                                                                                                              
                                The examiner argues that the subject matter of claims 5 and 6 is not supported                                                                         
                     by the specification as originally filed.  According to the examiner, there is no basis for a                                                                     
                     “native” substance in the specification and, therefore, the use of this term in claim 5                                                                           
                     constitutes the introduction of new matter.  Answer, p. 5.  We disagree.                                                                                          


                                We point out that it is not necessary for the specification to describe the claimed                                                                    

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