Ex Parte HOEGER et al - Page 3


                 Appeal No.  2001-1218                                                       Page 3                   
                 Application No.  08/727,798                                                                          

                                                   DISCUSSION                                                         
                 1.     Obviousness-Type Double Patenting                                                             
                        Claims 19-27 stand rejected under the judicially created doctrine of                          
                 obviousness-type double patenting as being unpatentable over claims 1-3 and 5-                       
                 25 of the ’468 patent and claims 1-7 of the ’932 patent.                                             
                        According to the rejection, the claims of the instant application are not                     
                 patentably distinct from the issued claims                                                           
                        because the instant intermediates in its protected form are obvious                           
                        variants of the final products in its unprotected form.  The protected                        
                        form of a peptide is but its final product wherein all of the protecting                      
                        groups have been removed.  One having ordinary skill in the art, at                           
                        the time the invention was made, knows that the final, unprotected                            
                        product is obtained from its protected intermediate wherein each of                           
                        the protecting groups have been removed with an appropriate                                   
                        reagent. . . .  Accordingly, the instant protected peptide compounds                          
                        are obvious variants of the unprotected ones.                                                 
                 Examiner’s Answer, pages 3-4.                                                                        
                        Appellants argue that the instantly claimed invention is not an obvious                       
                 extension of what is claimed in the ’468 and ’932 patents.  According to                             
                 appellants, while the instantly claimed compounds may be used to synthesize                          
                 the peptides claimed in the issued patents, other intermediates may also be                          
                 used, and the instantly claimed intermediates may also be used to arrive at                          
                 peptides other than those claimed in the issued patents.  See Appeal Brief,                          
                 pages 7-13.  We agree.                                                                               
                        The question that needs to be addressed is whether the instantly claimed                      
                 intermediates are an obvious variation of the patented claims.  In resolving that                    
                 question, the disclosure of the issued patents may not be used as prior art                          





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